INT317185

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Context Info
Confidence 0.47
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.51
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NAV1) cytoplasm (NAV1)
Anatomy Link Frequency
tooth pulp 2
NAV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nav1.7 43 100.00 Very High Very High Very High
Nav1.9 7 100.00 Very High Very High Very High
nav1.8 6 100.00 Very High Very High Very High
Inflammation 7 99.76 Very High Very High Very High
Pain 62 99.34 Very High Very High Very High
TRP channel 1 98.96 Very High Very High Very High
pulpitis 12 96.72 Very High Very High Very High
Face pain 11 92.48 High High
Neuropathic pain 3 90.56 High High
qutenza 1 86.16 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 7 99.76 Very High Very High Very High
Pain 48 99.34 Very High Very High Very High
Neuropathic Pain 12 98.72 Very High Very High Very High
Pulpitis 12 96.72 Very High Very High Very High
Facial Pain 11 92.48 High High
Burning Mouth Syndrome 39 84.32 Quite High
Inflammatory Pain 7 79.76 Quite High
Hypersensitivity 5 39.84 Quite Low
Rhinitis 1 35.04 Quite Low
Ganglion Cysts 4 6.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As we did not observe a significant change in TRPV1 immunoreactivity levels in painful dental pulpitis compared to non-painful tooth pulp [33], there appears to be differential expression of sodium and TRP channels in trigeminal pain disorders - further studies are required to confirm the increase of Nav1.7, Nav1.8 and Nav1.9 in inflammatory and TRPV1 in neuropathic trigeminal pain states.
Positive_regulation (required) of Positive_regulation (increase) of Nav1 in tooth pulp associated with pain, inflammation, trp channel, pulpitis, neuropathic pain, nav1.8, nav1.7 and nav1.9
1) Confidence 0.47 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2890014 Disease Relevance 1.51 Pain Relevance 2.08

General Comments

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