INT317186

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.90
Pain Relevance 3.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (BMS1) nucleus (BMS1) GTPase activity (BMS1)
Anatomy Link Frequency
nerve 1
BMS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 30 100.00 Very High Very High Very High
nav1.8 12 100.00 Very High Very High Very High
Nav1.7 86 98.90 Very High Very High Very High
qutenza 2 98.52 Very High Very High Very High
Pain 124 94.56 High High
pulpitis 24 82.40 Quite High
Neuropathic pain 6 78.60 Quite High
TRP channel 2 73.76 Quite High
Face pain 22 72.32 Quite High
IPN 14 68.00 Quite High
Disease Link Frequency Relevance Heat
Burning Mouth Syndrome 78 100.00 Very High Very High Very High
Pain 96 94.56 High High
Neuropathic Pain 24 84.68 Quite High
Pulpitis 24 82.40 Quite High
Facial Pain 22 72.32 Quite High
Hypersensitivity 10 68.84 Quite High
Inflammatory Pain 14 68.00 Quite High
Rhinitis 2 64.04 Quite High
INFLAMMATION 14 63.44 Quite High
Ganglion Cysts 8 35.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of Nav1.7 sodium channel in sub-epithelial nerve fibres did not change significantly in BMS in this study.
Neg (not) Regulation (change) of BMS in nerve associated with burning mouth syndrome, sodium channel and nav1.7
1) Confidence 0.04 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2890014 Disease Relevance 1.88 Pain Relevance 1.40
Our previous work also did not show a significant change in another sodium channel isoform Nav1.8 in BMS, whereas the levels of the heat and capsaicin receptor, transient receptor potential Vanilloid (TRPV1), were increased [31].
Regulation (change) of BMS associated with qutenza, burning mouth syndrome, sodium channel and nav1.8
2) Confidence 0.02 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2890014 Disease Relevance 2.02 Pain Relevance 1.77

General Comments

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