INT317315

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Snca, Psmb10) nucleus (Snca, Psmb10) mitochondrion (Snca)
cell morphogenesis (Psmb10) histone binding (Snca) enzyme binding (Snca)
Snca (Mus musculus)
Psmb10 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 11 18.12 Low Low
midbrain 2 9.76 Low Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Locus ceruleus 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
monoamine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 88 89.64 High High
Parkinson's Disease 49 85.52 High High
Stress 17 75.44 Quite High
Toxicity 7 74.40 Quite High
Aging 2 71.92 Quite High
Death 14 70.96 Quite High
Apoptosis 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tanaka et al. (2001) reported that expression of mutant alpha-synuclein significantly reduces chymotryptic-like, tryptic-like and post-acidic activities of the proteasome.
Gene_expression (expression) of mutant alpha-synuclein Negative_regulation (reduces) of proteasome
1) Confidence 0.00 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2890153 Disease Relevance 0.52 Pain Relevance 0

General Comments

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