INT317519

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin1, Oprm1) signal transduction (Oprm1) transport (Grin1)
enzyme binding (Grin1) signal transducer activity (Oprm1) cytoplasm (Grin1)
Anatomy Link Frequency
neuronal 2
Grin1 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 84 100.00 Very High Very High Very High
Glutamate 10 99.98 Very High Very High Very High
Morphine 77 98.48 Very High Very High Very High
antagonist 8 94.56 High High
Analgesic 19 74.08 Quite High
tolerance 28 73.28 Quite High
Kinase C 39 72.84 Quite High
Opioid 14 50.00 Quite Low
Periaqueductal grey 18 5.00 Very Low Very Low Very Low
tail-flick 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Intractable Pain 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In neuronal cells, the glutamate NMDAR is important for both the control and desensitization of the MOR [12], [13], [30].
NMDAR Positive_regulation (important) of Negative_regulation (desensitization) of MOR in neuronal associated with glutamate and opioid receptor
1) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 1.31

General Comments

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