INT317547

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Src, Grin1) cytoplasm (Src, Grin1) plasma membrane (Src, Grin1)
transport (Grin1) mitochondrion (Src) cell proliferation (Src)
Src (Mus musculus)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 77 98.68 Very High Very High Very High
tolerance 28 98.32 Very High Very High Very High
antagonist 8 89.56 High High
opioid receptor 84 89.12 High High
Opioid 14 75.00 Quite High
Intracerebroventricular 3 48.28 Quite Low
Glutamate 10 45.08 Quite Low
Analgesic 19 30.32 Quite Low
Periaqueductal grey 18 25.00 Low Low
Kinase C 39 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 18 25.00 Low Low
Nociception 7 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Intractable Pain 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and Src mediated potentiation of NMDAR activity, ultimately leading to morphine tolerance.
Src Positive_regulation (mediated) of Positive_regulation (potentiation) of NMDAR associated with tolerance and morphine
1) Confidence 0.17 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 0.72

General Comments

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