INT317569

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca, Src) enzyme binding (Prkca, Src) cytoplasm (Prkca, Src)
nucleus (Prkca, Src) plasma membrane (Prkca, Src) kinase activity (Prkca, Src)
Prkca (Mus musculus)
Src (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 39 100.00 Very High Very High Very High
Morphine 77 99.70 Very High Very High Very High
opioid receptor 84 94.12 High High
tolerance 28 84.08 Quite High
Analgesic 19 83.68 Quite High
antagonist 8 61.36 Quite High
Glutamate 10 50.48 Quite High
Opioid 14 50.00 Quite Low
Periaqueductal grey 18 5.00 Very Low Very Low Very Low
tail-flick 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Intractable Pain 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 10 nmol morphine dose promoted PKC-mediated phosphorylation of NMDAR1 Ser890 and Src-mediated phosphorylation of NMDAR2A Tyr1325.
PKC Positive_regulation (mediated) of Phosphorylation (phosphorylation) of Src associated with kinase c and morphine
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 1.25

General Comments

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