INT317741

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SOAT1) transferase activity, transferring acyl groups (SOAT1)
SOAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 33 91.16 High High
Fibrositis 54 79.84 Quite High
Pain 9 43.52 Quite Low
Inflammation 10 40.64 Quite Low
Osteoarthritis 54 40.32 Quite Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 145 82.00 Quite High
Fibromyalgia 54 79.84 Quite High
Pain 7 43.52 Quite Low
Fatigue 3 43.16 Quite Low
Leukemia 1 41.32 Quite Low
INFLAMMATION 13 40.64 Quite Low
Osteoarthritis 54 40.32 Quite Low
Disease 4 13.12 Low Low
Starvation 1 9.20 Low Low
Overweight 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When IL-6 binds to its receptor, a mechanism is triggered blocking Janus Kinase signal and activator of transcription (JAK/STAT) mediated transcription of IL-1 and TNF-?
Positive_regulation (mediated) of Transcription (transcription) of STAT
1) Confidence 0.49 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2891797 Disease Relevance 0.57 Pain Relevance 0.35
The activation of the signal transducer and activator of transcription (STAT) pathway by leptin was then monitored using an ELISA-based kit specific for STAT 1?
Positive_regulation (activation) of Transcription (transcription) of STAT
2) Confidence 0.16 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911905 Disease Relevance 0.05 Pain Relevance 0

General Comments

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