INT317798

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (HDAC10) nucleus (HDAC10) enzyme binding (HDAC10)
cytoplasm (HDAC10)
HDAC10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 89.60 High High
dexamethasone 1 88.16 High High
Inflammation 5 85.68 High High
corticosteroid 4 48.36 Quite Low
antagonist 3 19.92 Low Low
cINOD 1 5.08 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 1 97.56 Very High Very High Very High
Repression 2 88.92 High High
INFLAMMATION 6 85.68 High High
Asthma 53 82.72 Quite High
Disease 4 15.96 Low Low
Occupational Lung Diseases 10 5.00 Very Low Very Low Very Low
Pulmonary Disease 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 1 5.00 Very Low Very Low Very Low
Viral Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HDAC6 inactivation leads to hyperacetylation of heat shock protein 90 (Hsp90), a GR chaperone protein, and dissociation from the GR-hsp90 complex results in a reduction in nuclear translocation.21 HDAC10 is a member of the class II HDACs and is found to interact with other HDACs.
Localization (translocation.21) of HDAC10 associated with shock
1) Confidence 0.54 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2892049 Disease Relevance 0.65 Pain Relevance 0.21

General Comments

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