INT317818

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.18
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA2) plasma membrane (ITGA2)
Anatomy Link Frequency
chondrocytes 1
ITGA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 64 87.68 High High
Inflammation 9 81.56 Quite High
Neurotransmitter 3 71.92 Quite High
cytokine 3 42.00 Quite Low
alcohol 3 33.60 Quite Low
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
c fibre 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 144 96.48 Very High Very High Very High
Cancer 1 96.40 Very High Very High Very High
Osteoarthritis 71 87.68 High High
Apoptosis 11 82.92 Quite High
INFLAMMATION 11 81.56 Quite High
Aging 11 81.52 Quite High
Leukemia 1 43.80 Quite Low
Disease 4 30.00 Quite Low
Osteogenic Sarcomas 1 16.96 Low Low
Nicotine Addiction 3 15.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, our data suggest that EPH receptor A2, caveolins-1 and -2 and ITGA2 are under the control of COX-2 in sheared chondrocytes.
Regulation (under) of ITGA2 in chondrocytes
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012157 Disease Relevance 0.73 Pain Relevance 0.20
At control sites (BR?)
Regulation (control) of BR
2) Confidence 0.14 Published 2010 Journal Eur J Appl Physiol Section Body Doc Link PMC2892071 Disease Relevance 0.28 Pain Relevance 0
Control measurements (BR?)
Regulation (Control) of BR
3) Confidence 0.14 Published 2010 Journal Eur J Appl Physiol Section Body Doc Link PMC2892071 Disease Relevance 0.17 Pain Relevance 0.04
At control sites (BR?)
Regulation (control) of BR
4) Confidence 0.14 Published 2010 Journal Eur J Appl Physiol Section Body Doc Link PMC2892071 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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