INT317840

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ppa1)
Ppa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 5.00 Very Low Very Low Very Low
Antinociceptive 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Morphine 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 48 83.52 Quite High
Disorder Of Lipid Metabolism 28 77.60 Quite High
Stress 16 65.32 Quite High
Toxicity 4 53.44 Quite High
Hyperlipidemia 10 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Fungal Infection 4 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Pancreatitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The structural diversity of the isopropanoids which suppress cholesterol synthesis may be reconciled by their ability to increase pyrophosphatase activity, thus leading to the production of the endogenous, post-transcriptional regulator of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity (44).
Positive_regulation (increase) of pyrophosphatase
1) Confidence 0.04 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2892343 Disease Relevance 0.70 Pain Relevance 0
They increased microsomal geranyl pyrophosphate pyrophosphatase activity by 2-fold.
Positive_regulation (increased) of pyrophosphatase
2) Confidence 0.03 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2892343 Disease Relevance 0.56 Pain Relevance 0

General Comments

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