INT317895

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fos, Egr1) DNA binding (Fos, Egr1) transcription factor binding (Fos, Egr1)
intracellular (Egr1) cytoplasm (Egr1)
Anatomy Link Frequency
lung 2
Fos (Mus musculus)
Egr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 27 99.36 Very High Very High Very High
cytokine 3 98.84 Very High Very High Very High
chemokine 6 72.36 Quite High
Inflammatory response 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 99.36 Very High Very High Very High
Aids-related Complex 71 97.10 Very High Very High Very High
Alzheimer's Dementia 1 85.24 High High
Acute-phase Reaction 2 84.36 Quite High
Immune System Diseases 2 82.96 Quite High
Sprains And Strains 54 81.52 Quite High
Disease 11 81.08 Quite High
Cancer 15 47.92 Quite Low
Lung Cancer 13 5.00 Very Low Very Low Very Low
Toxicity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The top network in the B6 GMA-SS-exposed lung consisted primarily of decreased gene expression for dual specificity phosphatase 1 (DUSP1), a downregulator of MAPK signaling, transcriptional regulators EGR1, FOS, FOSB, and pro-inflammatory cytokine IL1?
FOS Regulation (regulators) of Transcription (transcriptional) of EGR1 in lung associated with inflammation, aids-related complex and cytokine
1) Confidence 0.41 Published 2010 Journal Respir Res Section Body Doc Link PMC2892448 Disease Relevance 1.03 Pain Relevance 0.17

General Comments

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