INT318094

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.24
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural constituent of ribosome (Rpl5) ribosome (Rpl5) intracellular (Rpl5)
cytoplasm (Rpl5) RNA binding (Rpl5) nucleus (Rpl5)
Anatomy Link Frequency
cornea 1
Rpl5 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 72.52 Quite High
anesthesia 2 44.64 Quite Low
ketamine 2 40.56 Quite Low
imagery 2 20.76 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 24 99.54 Very High Very High Very High
Keratitis 26 99.16 Very High Very High Very High
Corneal Neovascularization 4 98.56 Very High Very High Very High
Aspergillus Infection 6 95.40 Very High Very High Very High
Candida Infection 6 94.40 High High
Infection 4 93.52 High High
Chemical Burns 10 92.64 High High
Corneal Disease 14 88.88 High High
Disease 8 87.56 High High
Sprains And Strains 8 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of 8 HKGs (glyceraldehyde-3-phosphate dehydrogenase [GAPDH], beta-actin [ACTB], lactate dehydrogenase A [LDHA], ribosomal protein L5 [RPL5], ubiquitin C [UBC], peptidylprolyl isomerase A [PPIA], TATA-box binding protein [TBP1], and hypoxanthine guanine phosphoribosyl transferase [HPRT1]) in the cornea were measured at various time points by microarray hybridization or qRT–PCR and the data analyzed using geNorm and NormFinder.


Spec (analyzed) Gene_expression (Expression) of ribosomal protein L5 in cornea
1) Confidence 0.48 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2893048 Disease Relevance 0.84 Pain Relevance 0
In this paper, we establish models of experimental corneal neovascularization (CorNV), fungal keratitis (FK) and corneal wound in mice and study the expression patterns of three traditional HKGs (ACTB, lactate dehydrogenase [LDHA], and GAPDH), five new HKGs (ubiquitin C [UBC] [14], peptidylprolyl isomerase A [PPIA] [15], TATA-box binding protein [TBP] [16], hypoxanthine guanine phosphoribosyl transferase [HPRT1] [17], and ribosomal protein L5 [RPL5] [18]).
Gene_expression (expression) of ribosomal protein L5 associated with corneal neovascularization, injury and keratitis
2) Confidence 0.48 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2893048 Disease Relevance 0.40 Pain Relevance 0.04

General Comments

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