INT318217

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SIRT1, TP53) nucleoplasm (SIRT1, TP53) mitochondrion (SIRT1, TP53)
enzyme binding (SIRT1, TP53) cytoplasm (SIRT1, TP53) nucleolus (SIRT1, TP53)
SIRT1 (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 3 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 10 100.00 Very High Very High Very High
Aging 2 77.44 Quite High
Apoptosis 31 70.80 Quite High
Lymphopenia 1 63.12 Quite High
Death 1 59.64 Quite High
Necrosis 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low
Shock 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, SIRT1 can modulate cellular stress response and survival through regulation of p53 [20-22], NF-kB signaling [23] and FOXO transcription factors [24,25].
SIRT1 Regulation (regulation) of p53 associated with stress
1) Confidence 0.07 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2893521 Disease Relevance 0.43 Pain Relevance 0

General Comments

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