INT318236

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.59
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SIRT1) nucleoplasm (SIRT1) mitochondrion (SIRT1)
nuclear envelope (SIRT1) histone binding (SIRT1) enzyme binding (SIRT1)
SIRT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 5 90.64 High High
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 31 99.82 Very High Very High Very High
Shock 2 77.44 Quite High
Aging 66 69.36 Quite High
Stress 36 57.84 Quite High
Sprains And Strains 14 37.80 Quite Low
Starvation 23 5.00 Very Low Very Low Very Low
Coma 22 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that the physiological load imposed in amateur runners during marathon attenuates the extent of apoptosis and may interfere with sirtuin expression.



Spec (may) Negative_regulation (interfere) of Gene_expression (expression) of sirtuin associated with apoptosis
1) Confidence 0.42 Published 2010 Journal BMC Physiol Section Abstract Doc Link PMC2893521 Disease Relevance 0.45 Pain Relevance 0
The expression of Sirt2, a member of the Drosophila Sirtuin family [95], was strongly decreased in the mub, BG00817 and esg mutant backgrounds.
Negative_regulation (decreased) of Gene_expression (expression) of Sirtuin
2) Confidence 0.42 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912381 Disease Relevance 0.14 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox