INT318255

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 15
Disease Relevance 0
Pain Relevance 4.24

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cytoplasm (SDCCAG3)
SDCCAG3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Oxycodone 390 99.66 Very High Very High Very High
methadone 195 99.12 Very High Very High Very High
Opioid 45 79.64 Quite High
antidepressant 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reflex Sympathetic Dystrophy 45 15.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/L in samples collected downstream of the NY3 discharge (Figure S-3).
Gene_expression (discharge) of NY3
1) Confidence 0.05 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.10
Many of the samples of NY3 effluent (15 of 38, or 39%) had four or more pharmaceuticals with concentrations >10 ?
Gene_expression (samples) of NY3
2) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.38
The two pharmaceuticals (oxycodone and metaxalone) found in NY3 effluent at concentrations greater than 1000 ?
Gene_expression (found) of NY3 associated with oxycodone
3) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.33
g/L in a sample of NY3 effluent collected in February 2009 (butalbital 110 ?
Gene_expression (effluent) of NY3
4) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.30
g/L in a sample of NY3 effluent collected in February 2009 (butalbital 110 ?
Gene_expression (collected) of NY3
5) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.30
The two pharmaceuticals (oxycodone and metaxalone) found in NY3 effluent at concentrations greater than 1000 ?
Gene_expression (effluent) of NY3 associated with oxycodone
6) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.33
g/L) and NY3 effluent (450 ?
Gene_expression (effluent) of NY3
7) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0
Median total pharmaceutical concentrations in samples of NY2 and NY3 effluents were generally 30 to almost 500 times higher than total pharmaceutical concentrations typically found in the national effluent survey.
Gene_expression (effluents) of NY3
8) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0
Four pharmaceuticals (methadone, oxycodone, butalbital, and metaxalone) in samples of NY3 effluent had median concentrations ranging from 3.4 to >400 ?
Gene_expression (samples) of NY3 associated with oxycodone and methadone
9) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Abstract Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.53
Four pharmaceuticals (methadone, oxycodone, butalbital, and metaxalone) in samples of NY3 effluent had median concentrations ranging from 3.4 to >400 ?
Gene_expression (effluent) of NY3 associated with oxycodone and methadone
10) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Abstract Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.53
Maximum concentrations of oxycodone and metaxalone in samples of NY3 effluent were 1700 and 3800 ?
Gene_expression (effluent) of NY3 associated with oxycodone
11) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.53
Median concentrations for the five pharmaceuticals (butalbital, metaxalone, methadone, oxycodone, and phendimetrazine) most commonly detected in samples of NY3 effluent ranged from 0.5 to >400 ?
Gene_expression (effluent) of NY3 associated with oxycodone and methadone
12) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.48
Concentrations for six NY3 effluent samples quantified above 40 or 400 ?
Gene_expression (samples) of NY3
13) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0
However, 36% (84 of 236) of the individual pharmaceutical concentrations in samples of NY2 effluent and 61% (155 of 254) of the individual pharmaceutical concentrations in samples of NY3 effluent exceeded 1 ?
Gene_expression (effluent) of NY3
14) Confidence 0.04 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.32
Concentrations of Pharmaceuticals Downstream of NY1, NY2, and NY3 Effluents
Gene_expression (Concentrations) of NY3
15) Confidence 0.02 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.13

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