INT318278

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.47
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GABRB3) transport (GABRB3) plasma membrane (GABRB3)
transmembrane transport (GABRB3)
Anatomy Link Frequency
cortex 2
GABRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 108 99.00 Very High Very High Very High
GABAergic 207 95.88 Very High Very High Very High
fluoxetine 6 49.92 Quite Low
Cannabinoid receptor 42 5.00 Very Low Very Low Very Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 51 98.64 Very High Very High Very High
Lifespan 81 76.20 Quite High
Amblyopia 21 67.08 Quite High
Anxiety Disorder 3 30.08 Quite Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Cataract 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in expression of GABAA?
Regulation (Changes) of Gene_expression (expression) of GABAA
1) Confidence 0.14 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2893712 Disease Relevance 0.30 Pain Relevance 0.22
It seems likely that the high levels of GAD65 and GABAA?
Spec (likely) Regulation (likely) of Gene_expression (levels) of GABAA
2) Confidence 0.12 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2893712 Disease Relevance 0 Pain Relevance 0.31
In adult visual cortex, activity regulates GABAA receptor expression (Hendry et al., 1994) and during aging the loss of orientation tuning in visual cortical receptive fields (Leventhal et al., 2003) and changes in visual perception (Betts et al., 2005) have been linked with an overall loss of GABA.
Regulation (regulates) of Gene_expression (expression) of GABAA receptor in cortex associated with gaba and aging
3) Confidence 0.07 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2893712 Disease Relevance 0.17 Pain Relevance 0.24

General Comments

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