INT318303

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
nucleus (Myoz1) cell-cell signaling (IL2)
Anatomy Link Frequency
T-lymphocyte 3
Myoz1 (Mus musculus)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 16 93.80 High High
withdrawal 1 8.00 Low Low
Infliximab 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Etanercept 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Leflunomide 4 5.00 Very Low Very Low Very Low
Parenteral administration 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 30 96.68 Very High Very High Very High
Glomerulonephritis 10 77.20 Quite High
Hepatotoxicity 2 72.92 Quite High
Autoimmune Disease 8 72.56 Quite High
Vasculitis 60 61.92 Quite High
Hyperplasia 1 50.44 Quite High
Reprotox - General 3 1 37.20 Quite Low
Lymphatic System Cancer 3 36.52 Quite Low
Systemic Lupus Erythematosus 7 34.56 Quite Low
Malignant Neoplastic Disease 1 33.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cyclosporin and tacrolimus are both calcineurin inhibitors which inhibit T-lymphocyte signal transduction and IL-2 transcription.
Negative_regulation (inhibitors) of calcineurin in T-lymphocyte Negative_regulation (inhibit) of Transcription (transcription) of IL-2 in T-lymphocyte
1) Confidence 0.00 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2893757 Disease Relevance 0.75 Pain Relevance 0.21

General Comments

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