INT31843

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Prl) plasma membrane (Grpr) signal transducer activity (Grpr)
Anatomy Link Frequency
lactotrope 2
Grpr (Rattus norvegicus)
Prl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 4 100.00 Very High Very High Very High
Analgesic 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 4 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results show that bombesin given intravenously acts as an inhibitor of PRL secretion and suggests that it does not act on the lactotrope itself but rather by an increase of the inhibitory dopaminergic tone.
bombesin Negative_regulation (inhibitor) of Localization (secretion) of PRL in lactotrope
1) Confidence 0.03 Published 1988 Journal Life Sci. Section Abstract Doc Link 2904106 Disease Relevance 0.17 Pain Relevance 0.17
Intravenously administered bombesin lowered basal PRL levels in conscious male rats and prevented the morphine, bremazocine and stress-induced PRL secretion.
bombesin Negative_regulation (prevented) of Localization (secretion) of PRL associated with stress and morphine
2) Confidence 0.03 Published 1988 Journal Life Sci. Section Abstract Doc Link 2904106 Disease Relevance 0.17 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox