INT318472

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (CA2) Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1)
signal transducer activity (OPRM1) response to stress (CA2) cytoplasm (CA2)
CA2 (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 27 100.00 Very High Very High Very High
Analgesic 12 96.88 Very High Very High Very High
Opioid 27 96.04 Very High Very High Very High
opioid receptor 34 74.00 Quite High
action potential duration 2 21.60 Low Low
dorsal root ganglion 7 9.04 Low Low
Hyperalgesia 16 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
narcan 11 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 3 43.84 Quite Low
Ganglion Cysts 7 9.04 Low Low
Nociception 3 7.80 Low Low
Hyperalgesia 19 5.00 Very Low Very Low Very Low
Neuroblastoma 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Post Operative Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the robust effect of morphine on MOR1K-dependent Ca2+ and NO release, in conjunction with a primary role of VGCC in mediating the analgesic effects of opioids [17,18] and the observation that MOR1K couples to G?
Ca2 Regulation (effect) of MOR1K associated with analgesic, opioid and morphine
1) Confidence 0.17 Published 2010 Journal Mol Pain Section Body Doc Link PMC2894766 Disease Relevance 0 Pain Relevance 0.51

General Comments

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