INT318480

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) plasma membrane (LTB4R) nucleus (IRF6)
DNA binding (IRF6) signal transducer activity (LTB4R) cytoplasm (IRF6)
IRF6 (Homo sapiens)
LTB4R (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 62 87.44 High High
dexamethasone 42 83.84 Quite High
Inflammation 56 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Occupational Lung Diseases 74 99.76 Very High Very High Very High
Asthma 202 97.28 Very High Very High Very High
INFLAMMATION 56 5.00 Very Low Very Low Very Low
Nicotine Addiction 8 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Rhinitis 6 5.00 Very Low Very Low Very Low
Pulmonary Disease 4 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The LTB4 production induced by LPS is shown as increments in LTB4 above baseline (Figure 2B).
LPS Positive_regulation (induced) of Gene_expression (production) of LTB4
1) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 0.81 Pain Relevance 0.14
LPS induced LTB4 generation in all three groups (p < 0.05), but the increase in LTB4 in severe asthma patients was 5-fold greater than in non-severe asthmatics (p < 0.05; Figure 2B).


LPS Positive_regulation (induced) of Gene_expression (generation) of LTB4 associated with asthma and occupational lung diseases
2) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 0.82 Pain Relevance 0.15

General Comments

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