INT318491

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 6.14
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) cell adhesion (FPR2) plasma membrane (FPR2)
nucleus (IRF6) DNA binding (IRF6) signal transducer activity (FPR2)
Anatomy Link Frequency
lung 1
neutrophils 1
IRF6 (Homo sapiens)
FPR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 126 99.78 Very High Very High Very High
Inflammation 168 95.80 Very High Very High Very High
corticosteroid 186 90.80 High High
cytokine 18 84.20 Quite High
agonist 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Versed 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 606 99.48 Very High Very High Very High
Occupational Lung Diseases 222 97.88 Very High Very High Very High
INFLAMMATION 168 95.80 Very High Very High Very High
Adhesions 18 78.88 Quite High
Rhinitis 18 74.40 Quite High
Hypersensitivity 6 73.36 Quite High
Systemic Sclerosis 6 53.28 Quite High
Pulmonary Disease 12 52.32 Quite High
Inflammatory Bowel Disease 6 46.16 Quite Low
Nicotine Addiction 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, dexamethasone suppressed LPS-induced increases in LXA4 in all groups.
LPS Positive_regulation (increases) of LXA4 associated with dexamethasone
1) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 1.33 Pain Relevance 0.59
LXA4 induced by LPS was highest in normal subjects and lowest in severe asthmatics (p < 0.01).
LPS Positive_regulation (induced) of LXA4 associated with occupational lung diseases
2) Confidence 0.10 Published 2010 Journal Respir Res Section Abstract Doc Link PMC2894769 Disease Relevance 1.00 Pain Relevance 0.23
There was a small but significant increase in LPS-induced LXA4 levels in all three groups (Figure 1B), with the lowest amounts in severe compared to non-severe asthma (p < 0.01) and to normal subjects (p < 0.001).
LPS Positive_regulation (induced) of LXA4 associated with asthma
3) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 0.94 Pain Relevance 0.03
There was a negative correlation between baseline LXA4 levels in asthmatic patients and the percentage of neutrophils in the BAL (rs = - 0.42, p < 0.05), and a positive correlation between LPS-induced LXA4 levels from asthmatic patients and FEV1 (% predicted; r = 0.60, p < 0.01).
LPS Positive_regulation (induced) of LXA4 in neutrophils associated with asthma
4) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 0.89 Pain Relevance 0.03
Dexamethasone inhibited LPS-induced LTB4 and LXA4, with lesser suppression of LTB4 in severe asthma patients (p < 0.05).
LPS Positive_regulation (induced) of LXA4 associated with asthma and dexamethasone
5) Confidence 0.10 Published 2010 Journal Respir Res Section Abstract Doc Link PMC2894769 Disease Relevance 0.99 Pain Relevance 0.23
In support of the protective effect of LXA4, we found a positive correlation between LPS-induced LXA4 and lung function as represented by FEV1.
LPS Positive_regulation (induced) of LXA4 in lung
6) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 0.99 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox