INT318499

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 4.89
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (AIF1) plasma membrane (AIF1) cytoskeleton (AIF1)
nucleus (AIF1) response to stress (AIF1) cytoplasm (AIF1)
Anatomy Link Frequency
macrophage 1
microglia 1
AIF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 36 100.00 Very High Very High Very High
corticosteroid 31 99.98 Very High Very High Very High
Neurobehavioral 14 82.72 Quite High
dexamethasone 21 72.08 Quite High
chemokine 14 59.20 Quite High
cytokine 25 58.60 Quite High
Central nervous system 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
glial activation 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 40 100.00 Very High Very High Very High
Asthma 101 99.00 Very High Very High Very High
Targeted Disruption 24 97.52 Very High Very High Very High
Hepatitis C Virus Infection 378 96.48 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 146 91.76 High High
Drug Induced Neurotoxicity 24 79.04 Quite High
Inflammatory Bowel Disease 1 76.60 Quite High
Pulmonary Disease 2 72.96 Quite High
Systemic Sclerosis 1 72.44 Quite High
Injury 22 66.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphological analysis at day 14 post-implantation disclosed increased immunoreactivity of GFAP, an astrocyte marker, and Iba-1, a microglia/macrophage marker, in the right striatum of Vpr-transgenic mice receiving HCV core protein implantation (Figure 7Aiv and v).
Regulation (immunoreactivity) of Iba-1 in macrophage associated with targeted disruption and hepatitis c virus infection
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 1.82 Pain Relevance 0.10
Morphological analysis at day 14 post-implantation disclosed increased immunoreactivity of GFAP, an astrocyte marker, and Iba-1, a microglia/macrophage marker, in the right striatum of Vpr-transgenic mice receiving HCV core protein implantation (Figure 7Aiv and v).
Regulation (immunoreactivity) of Iba-1 in microglia associated with targeted disruption and hepatitis c virus infection
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 1.82 Pain Relevance 0.10
In summary, we demonstrate impaired corticosteroid modulation of the pro-inflammatory lipid mediator LTB4 but not of the anti-inflammatory lipoxin, LXA4, in AMs of severe asthma.
Regulation (modulation) of anti-inflammatory lipoxin associated with asthma, corticosteroid and inflammation
3) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 1.26 Pain Relevance 0.40

General Comments

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