INT318545

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adamts1) extracellular region (Adamts1) proteinaceous extracellular matrix (Adamts1)
Anatomy Link Frequency
blood vessel 1
Adamts1 (Mus musculus)
Tsp1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 220 98.08 Very High Very High Very High
Prostate Cancer 50 72.48 Quite High
Metastasis 12 40.80 Quite Low
Malignant Neoplastic Disease 6 40.48 Quite Low
Vascular Tissue Neoplasms 2 37.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Instead, the total protein levels of detected TSP1 were markedly affected by ADAMTS1 levels.
ADAMTS1 Regulation (affected) of TSP1
1) Confidence 0.20 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2894797 Disease Relevance 0.70 Pain Relevance 0
Thus, the ADAMTS1-mediated effect on TSP1 levels could be a possible mechanism responsible for the switch in blood vessel morphology observed.
ADAMTS1 Regulation (effect) of TSP1 in blood vessel
2) Confidence 0.20 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2894797 Disease Relevance 0.69 Pain Relevance 0

General Comments

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