INT318547

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adamts1) extracellular region (Adamts1) proteinaceous extracellular matrix (Adamts1)
Adamts1 (Mus musculus)
Tsp1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 220 94.40 High High
Prostate Cancer 50 82.48 Quite High
Metastasis 12 50.80 Quite High
Vascular Tissue Neoplasms 2 34.20 Quite Low
Malignant Neoplastic Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Downregulation of ADAMTS1 in LNCaP resulted in increased levels of TSP1 (Figure 6A, B), and upregulation of ADAMTS1 in LNCaP-19 was associated with decreased levels of TSP1 (Figure 6C, D).


Negative_regulation (Downregulation) of ADAMTS1 Positive_regulation (increased) of TSP1
1) Confidence 0.35 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2894797 Disease Relevance 0.87 Pain Relevance 0
Downregulation of ADAMTS1 in LNCaP resulted in increased levels of TSP1 (Figure 6A, B), and upregulation of ADAMTS1 in LNCaP-19 was associated with decreased levels of TSP1 (Figure 6C, D).


Negative_regulation (Downregulation) of ADAMTS1 Positive_regulation (levels) of TSP1
2) Confidence 0.35 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2894797 Disease Relevance 0.87 Pain Relevance 0

General Comments

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