INT318712

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Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.20
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sept3) cytoskeleton (Sept3) cell cycle (Sept3)
cytoplasm (Sept3)
Sept3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 19 100.00 Very High Very High Very High
cytokine 3 100.00 Very High Very High Very High
Multiple sclerosis 1 96.56 Very High Very High Very High
Central nervous system 3 94.56 High High
Serotonin 16 66.80 Quite High
Inflammatory mediators 1 55.56 Quite High
depression 13 43.84 Quite Low
antidepressant 12 39.68 Quite Low
sSRI 11 30.96 Quite Low
headache 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 23 100.00 Very High Very High Very High
Disease 3 99.52 Very High Very High Very High
Multiple Sclerosis 3 96.56 Very High Very High Very High
Demyelinating Disease 1 95.44 Very High Very High Very High
Erectile Dysfunction 140 94.40 High High
Periodontal Disease 33 83.92 Quite High
Periodontitis 29 75.12 Quite High
Hypercalcemia 3 71.56 Quite High
Disease Progression 1 70.64 Quite High
Hypoactive Sexual Desire Disorder 2 66.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SEP3: “Did your erection last long enough for you to have a successful intercourse?”
Gene_expression (erection) of SEP3
1) Confidence 0.34 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2939761 Disease Relevance 0.59 Pain Relevance 0
Similarly, the mean percentage of per-patient SEP3 affirmative responses was higher in treated men (67.2%, 72.8%, and 36.7% for 5 mg, 10 mg, and placebo groups, respectively).42

Rajfer 2007: daily tadalafil for ED

Gene_expression (responses) of SEP3 associated with erectile dysfunction
2) Confidence 0.34 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2939761 Disease Relevance 0.31 Pain Relevance 0
Venlafaxine ameliorated the clinical symptoms of the disease possibly by suppressed production of pro-inflammatory cytokines interleukin-12 (IL-12), p40, TNF-?
Gene_expression (production) of p40 associated with inflammation, disease and cytokine
3) Confidence 0.19 Published 2010 Journal J Negat Results Biomed Section Body Doc Link PMC2895576 Disease Relevance 1.30 Pain Relevance 0.35

General Comments

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