INT318922

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (XIAP, COMMD1) cytosol (XIAP) nucleolus (COMMD1)
nucleus (COMMD1) intracellular (XIAP) ligase activity (XIAP)
XIAP (Homo sapiens)
COMMD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 11 100.00 Very High Very High Very High
Targeted Disruption 2 96.56 Very High Very High Very High
Death 2 58.40 Quite High
Cirrhosis 2 57.64 Quite High
Hepatitis 1 57.08 Quite High
Hepatolenticular Degeneration 35 50.00 Quite Low
Disease 8 14.04 Low Low
Dystonia 4 5.00 Very Low Very Low Very Low
Tremor 3 5.00 Very Low Very Low Very Low
Hypokinesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, XIAP (X-linked Inhibitor of Apoptosis) has been observed to negatively regulate COMMD1 protein levels by the formation of K48 polyubiquitin chains on COMMD1 that promote its degradation [12].
XIAP Regulation (regulate) of COMMD1 associated with apoptosis
1) Confidence 0.09 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2896338 Disease Relevance 0.37 Pain Relevance 0

General Comments

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