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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ATP7B) Golgi apparatus (ATP7B) cytoplasmic membrane-bounded vesicle (ATP7B)
transmembrane transport (ATP7B) cytoplasm (ATP7B)
ATP7B (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 20 97.22 Very High Very High Very High
Bile 1 73.24 Quite High
Pain scale 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dementia 48 100.00 Very High Very High Very High
Hepatolenticular Degeneration 35 97.58 Very High Very High Very High
Pain 25 97.22 Very High Very High Very High
Disease 12 93.52 High High
Cognitive Disorder 7 80.84 Quite High
Apoptosis 11 50.00 Quite Low
Death 2 50.00 Quite Low
Hepatitis 1 29.44 Quite Low
Cirrhosis 2 28.32 Quite Low
Dystonia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although WD is an established monogenic disorder, heterogeneity in phenotype is observed even among patients harboring mutations in ATP7B that would affect the mutant protein similarly (e.g. different truncation mutations in the same region of the gene or exactly same set of mutations in two sibs); no particular phenotype can be attributed to a particular mutation [5].
Regulation (affect) of ATP7B associated with hepatolenticular degeneration
1) Confidence 0.40 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2896338 Disease Relevance 0.32 Pain Relevance 0.04
A poor association of informant report with self report and direct observation has also been described in the assessment of pain in the RCF setting.17 Our data emphasise that the perspectives of PWD and their informants are not necessarily congruent and that factors affecting the relationship between informants and PWD may influence informants' perceptions of the QoL of PWD.
Regulation (affecting) of PWD associated with pain and dementia
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001486 Disease Relevance 0.80 Pain Relevance 0.25

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