INT318962

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.50
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Mecp2) embryo development (Mecp2) DNA binding (Mecp2)
protein complex (Mecp2) response to stress (Mecp2) cytoplasm (Mecp2)
Anatomy Link Frequency
brains 2
Mecp2 (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 95 99.92 Very High Very High Very High
tetrodotoxin 1 69.00 Quite High
sodium channel 1 68.16 Quite High
midbrain 6 32.32 Quite Low
Neurotransmitter 1 8.12 Low Low
Eae 4 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
interneuron 2 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retts Disease 80 86.44 High High
Aids-related Complex 4 81.92 Quite High
Stress 6 53.76 Quite High
Anxiety Disorder 24 49.88 Quite Low
Sprains And Strains 3 33.56 Quite Low
Disease 11 5.00 Very Low Very Low Very Low
Autism 7 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Intellectual Impairment 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, we observed decreased expression of synaptic proteins in brains of Mecp2?
Negative_regulation (decreased) of Gene_expression (expression) of Mecp2 in brains
1) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2902516 Disease Relevance 0.33 Pain Relevance 0
The steady state level of PSD95 and Syp mRNAs in Mecp2?
Negative_regulation (level) of Gene_expression (mRNAs) of Mecp2
2) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2902516 Disease Relevance 0.17 Pain Relevance 0
Synaptic maturation and elimination at excitatory projections to the LA in Mecp2 deficient mice
Negative_regulation (deficient) of Gene_expression (deficient) of Mecp2 associated with amygdala
3) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2896423 Disease Relevance 0 Pain Relevance 0.70

General Comments

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