INT319048

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.87
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (WT1) nucleolus (WT1) RNA binding (WT1)
nucleus (WT1) intracellular (WT1) cytoplasm (WT1)
Anatomy Link Frequency
dendritic cells 1
GBM 1
WT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 66.52 Quite High
cytokine 15 63.92 Quite High
chemokine 13 43.20 Quite Low
Freund adjuvant 1 27.28 Quite Low
palliative 1 23.60 Low Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioblastoma 38 99.78 Very High Very High Very High
Myeloid Leukemia 41 98.14 Very High Very High Very High
Cancer 153 94.36 High High
Anaplastic Astrocytoma 1 84.56 Quite High
Infection 3 83.40 Quite High
Fever 3 79.68 Quite High
Glioma 50 78.16 Quite High
Hematological Disease 1 77.32 Quite High
Disease 31 75.64 Quite High
Myelodysplastic Syndromes 4 70.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another study also investigated preparation of monocyte-derived dendritic cells in AML; these authors combined ex vivo generation of the cells followed by cryopreservation before transfection of WT1 mRNA by electroporation [87].
Transcription (transfection) of WT1 in dendritic cells associated with myeloid leukemia
1) Confidence 0.56 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896720 Disease Relevance 1.03 Pain Relevance 0.12
Other antigens associated with GBM have been described including EphA2, survivin, WT1, SOX2, SOX11, MAGE1, AIM2, and SART1 [18].
Transcription (described) of WT1 in GBM associated with glioblastoma
2) Confidence 0.21 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2952949 Disease Relevance 0.84 Pain Relevance 0.03

General Comments

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