INT319156

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hdac1) nucleus (Hdac1) enzyme binding (Hdac1)
DNA binding (Hdac1) protein complex (Hdac1) transcription factor binding (Hdac1)
Anatomy Link Frequency
embryos 4
oocytes 2
Hdac1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 9 74.24 Quite High
Ovarian Hyperstimulation Syndrome 6 72.56 Quite High
Dislocations 6 20.00 Low Low
Cancer 3 5.00 Very Low Very Low Very Low
Reprotox - General 3 3 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 3 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reduced level of HDAC1 protein expression in nuclei of IVM 2-cell embryos suggested that IVM affected the HDAC1 protein syntheses and might interrupt its nucleus-cytoplasm distributions at this stage of embryos [20].
Negative_regulation (reduced) of Gene_expression (expression) of HDAC1 protein in embryos
1) Confidence 0.39 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2896857 Disease Relevance 0 Pain Relevance 0
Expression of HDAC1 mRNA in MII oocytes and two-cell embryos decreased in the IVM group.
Negative_regulation (decreased) of Gene_expression (Expression) of HDAC1 mRNA in embryos
2) Confidence 0.39 Published 2010 Journal Obstetrics and Gynecology International Section Abstract Doc Link PMC2896857 Disease Relevance 0.22 Pain Relevance 0
We determined the expression and distribution of GCN5, HDAC1, and Ac-H3 in metaphase II oocytes matured in vitro and in vivo.
Spec (determined) Negative_regulation (determined) of Spec (determined) Gene_expression (expression) of HDAC1 in oocytes
3) Confidence 0.39 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2896857 Disease Relevance 0 Pain Relevance 0

General Comments

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