INT319160

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hist1h3f) molecular_function (Hist1h3f) biological_process (Hist1h3f)
Anatomy Link Frequency
oocytes 1
Hist1h3f (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 6 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 26 93.68 High High
Cancer 23 87.24 High High
Polycystic Ovary Syndrome 3 84.76 Quite High
Ovarian Hyperstimulation Syndrome 2 83.08 Quite High
Stomach Cancer 36 75.00 Quite High
Fibrosis 6 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Aggression 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VPA induced dynamic modulation of histone H3 and ?
Regulation (modulation) of histone H3
1) Confidence 0.07 Published 2010 Journal J Exp Clin Cancer Res Section Abstract Doc Link PMC2994814 Disease Relevance 0.45 Pain Relevance 0
To investigate the influences of IVM on epigenetic reprogramming and to search for the possible reasons for the lower rates of fertilization and cleavage in IVM oocytes, we examined the expression of two enzymes controlling histone acetylation, histone acetyltransferase GCN5 (GCN5) and histone deacetylase 1 (HDAC1), as well as their common target, acetyl-histone H3 (Ac-H3), in mouse metaphase II (MII) oocytes and preimplantation embryos.
Spec (examined) Regulation (target) of histone H3 in oocytes
2) Confidence 0.06 Published 2010 Journal Obstetrics and Gynecology International Section Abstract Doc Link PMC2896857 Disease Relevance 0.25 Pain Relevance 0

General Comments

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