INT31921

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Context Info
Confidence 0.17
First Reported 1988
Last Reported 1995
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Npr1) intracellular (Npr1)
Anatomy Link Frequency
brain 2
Npr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 100.00 Very High Very High Very High
Kappa opioid receptor 2 99.80 Very High Very High Very High
narcan 4 99.06 Very High Very High Very High
gABA 4 98.24 Very High Very High Very High
tetrodotoxin 2 95.68 Very High Very High Very High
Enkephalin 6 95.40 Very High Very High Very High
nMDA receptor 4 92.40 High High
Dopamine 5 86.28 High High
agonist 3 81.40 Quite High
opioid receptor 3 78.76 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibitors of NO synthase (NG-nitro- and NG-amino-L-arginine) and guanylate cyclase (LY83583) elevated release.
Negative_regulation (Inhibitors) of Localization (release) of guanylate cyclase
1) Confidence 0.17 Published 1995 Journal Neurosci. Lett. Section Abstract Doc Link 7637891 Disease Relevance 0 Pain Relevance 0.55
Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanate.
Negative_regulation (inhibition) of Localization (release) of cyclase in brain associated with neurotransmitter, narcan and kappa opioid receptor
2) Confidence 0.03 Published 1988 Journal Eur. J. Pharmacol. Section Title Doc Link 2906610 Disease Relevance 0 Pain Relevance 0.96

General Comments

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