INT319229

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.92
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) mRNA processing (SNRNP70) RNA binding (SNRNP70)
nucleus (SNRNP70)
SNRNP70 (Homo sapiens)
Aia1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
aspirin 58 91.16 High High
metalloproteinase 3 47.04 Quite Low
Calcium channel 10 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 152 100.00 Very High Very High Very High
Hypersensitivity 7 91.84 High High
Occupational Lung Diseases 11 82.16 Quite High
Coagulation Disorder 1 66.56 Quite High
Disease 8 64.16 Quite High
Obesity 8 60.24 Quite High
Nicotine Addiction 8 57.24 Quite High
Alzheimer's Dementia 3 52.08 Quite High
Stress 1 25.76 Quite Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, we found 18 SNPs and 4 haplotypes of FSIP1 showing associations with AIA initially, and after multiple testing correction, one SNP, rs7179742 showed significant association with AIA.
SNP Binding (association) of AIA associated with asthma
1) Confidence 0.00 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2896935 Disease Relevance 1.35 Pain Relevance 0.25
Interestingly, analysis revealed that a SNP in intron (rs192808C > T; OR = 2.88, 95% CI = 1.60-5.17, P = 0.0004, Pcorr = 0.0029 in co-dominant model), which was more frequent in AIA patients than in ATA controls (0.103 in AIA patients and 0.045 in ATA patients) (Table 2), was significantly associated with the risk of AIA even after multiple testing corrections.
SNP Binding (associated) of AIA associated with asthma
2) Confidence 0.00 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2954844 Disease Relevance 1.57 Pain Relevance 0

General Comments

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