INT31926

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Context Info
Confidence 0.00
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Agtr2) plasma membrane (Agtr2) transcription factor binding (Agtr2)
signal transducer activity (Agtr2)
Anatomy Link Frequency
nerve 2
Agtr2 (Mus musculus)
Pain Link Frequency Relevance Heat
noradrenaline 1 98.20 Very High Very High Very High
antagonist 5 90.00 High High
Potency 1 57.92 Quite High
Clonidine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 3 98.74 Very High Very High Very High
Hypotension 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reflex tachycardia is weak or absent, owing to the following mechanisms: (1) The absence of presynaptic alpha 2-receptor blockade, thus preventing the accelerated release of noradrenaline from the nerve endings; and (2) the blockade of central alpha 1-adrenoceptors, causing a blunting of the reflex tachycardia via the baroreceptor mechanism.
Negative_regulation (absence) of Negative_regulation (blockade) of 2-receptor in nerve associated with heart rate under development and noradrenaline
1) Confidence 0.00 Published 1988 Journal J Hypertens Suppl Section Abstract Doc Link 2906698 Disease Relevance 0.19 Pain Relevance 0.20

General Comments

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