INT319315

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ap2a2) Golgi apparatus (Htt) endoplasmic reticulum (Htt)
mitochondrion organization (Htt) embryo development (Htt) protein complex (Htt)
Anatomy Link Frequency
vesicles 1
Ap2a2 (Mus musculus)
Htt (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 1 86.44 High High
Neurotransmitter 6 86.04 High High
Glutamate 117 50.64 Quite High
chemokine 9 38.84 Quite Low
Inflammatory response 3 37.68 Quite Low
Hippocampus 24 5.00 Very Low Very Low Very Low
Central nervous system 7 5.00 Very Low Very Low Very Low
nMDA receptor 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 13 94.20 High High
Neurological Disease 2 60.64 Quite High
Targeted Disruption 78 59.44 Quite High
Stress 24 44.20 Quite Low
INFLAMMATION 7 37.28 Quite Low
Death 10 35.36 Quite Low
Apoptosis 6 28.24 Quite Low
Aging 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 12 5.00 Very Low Very Low Very Low
Shock 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The AP2A2 protein, together with Huntingtin, interacts with the protein Clathrin in the process of endocytosis of membrane vesicles [23].
AP2A2 protein Binding (interacts) of Huntingtin in vesicles
1) Confidence 0.28 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2896956 Disease Relevance 0.64 Pain Relevance 0.11

General Comments

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