INT319381

Context Info Confidence 0.13 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.01 Pain Relevance 0.18

extracellular space (IL33) extracellular region (IL33)

ST2 (Homo sapiens) IL33 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammatory response 2 99.60 Inflammation 25 75.96 chemokine 6 70.44 aspirin 5 5.00 fibrosis 2 5.00 lidocaine 1 5.00 cytokine 1 5.00 cocaine 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 27 99.24 Rhinitis 62 98.72 Asthma 17 94.76 Eczema 31 91.12 Nasal Polyps 6 66.80 Chronic Sinusitis 14 65.96 Anaphylaxis 1 53.84 Eosinophilic Esophagitis 5 16.52 Disease 23 6.64 Polyps 13 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

IL1RL1 (ST2) was recently identified as the receptor for IL33 (a member of the IL1 family, although the IL33 gene is located on a separate chromosome).

ST2 Binding (receptor) of IL33

1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.01 Pain Relevance 0.18

General Comments

This test has worked.