INT319398

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.93
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRISP3) proteinaceous extracellular matrix (CRISP3) molecular_function (CRISP3)
CRISP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 20 87.44 High High
Inflammation 100 70.96 Quite High
Inflammatory response 8 33.40 Quite Low
cytokine 4 19.92 Low Low
chemokine 24 12.00 Low Low
fibrosis 8 10.68 Low Low
lidocaine 4 5.00 Very Low Very Low Very Low
cocaine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilic Esophagitis 20 99.36 Very High Very High Very High
Polyps 52 98.48 Very High Very High Very High
Disease 92 96.84 Very High Very High Very High
Rhinitis 248 92.60 High High
Adhesions 8 85.28 High High
Chronic Sinusitis 56 83.76 Quite High
INFLAMMATION 108 70.96 Quite High
Asthma 68 69.20 Quite High
Eczema 124 68.48 Quite High
Anaphylaxis 4 59.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to EMR3 and EMR1, our exon array data showed decreased transcription of CRISP3 and CRISP2.
Transcription (transcription) of CRISP3
1) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.86 Pain Relevance 0.04
Although the function(s) of these molecules is obscure, decreased transcription of CRISP3 is observed in EE and associated with the presence of IL13 [20].
Transcription (transcription) of CRISP3 associated with eosinophilic esophagitis
2) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.86 Pain Relevance 0.03
In agreement with the exon array data, CCL13, CCL18, EMR3, and IL1RL1 transcription was increased while CRISP3 transcription was decreased in inflamed mucosa and polyp tissue from aCRSwNP subjects.
Transcription (transcription) of CRISP3 associated with polyps
3) Confidence 0.38 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.51 Pain Relevance 0.04
Interestingly, these results were often opposite to those of Liu et al., who reported increased transcription of AZGP1, STATH, PIP, and CRISP3 [10].
Transcription (transcription) of CRISP3
4) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.69 Pain Relevance 0.14

General Comments

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