INT319424

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.17
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (EMR3) extracellular region (EMR3) plasma membrane (EMR3)
signal transducer activity (EMR3)
Anatomy Link Frequency
eosinophil 1
EMR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 75 99.08 Very High Very High Very High
aspirin 15 76.20 Quite High
Inflammatory response 6 61.52 Quite High
chemokine 18 32.36 Quite Low
fibrosis 6 5.00 Very Low Very Low Very Low
lidocaine 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 81 99.08 Very High Very High Very High
Adhesions 6 99.00 Very High Very High Very High
Rhinitis 186 98.56 Very High Very High Very High
Polyps 39 96.84 Very High Very High Very High
Asthma 51 91.96 High High
Anaphylaxis 3 87.60 High High
Eczema 93 86.72 High High
Disease 69 81.60 Quite High
Chronic Sinusitis 42 70.32 Quite High
Eosinophilic Esophagitis 15 63.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whether EMR3 and EMR1 transcription per eosinophil is increased in aCRSwNP or the increased transcription reflects elevated numbers of infiltrating eosinophils is unknown.
Transcription (transcription) of EMR3 in eosinophil
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.71 Pain Relevance 0.04
Increased transcription of both EMR3 and EMR1 was observed in our exon array data.
Transcription (transcription) of EMR3
2) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.91 Pain Relevance 0.08
In agreement with the exon array data, CCL13, CCL18, EMR3, and IL1RL1 transcription was increased while CRISP3 transcription was decreased in inflamed mucosa and polyp tissue from aCRSwNP subjects.
Transcription (transcription) of EMR3 associated with polyps
3) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.55 Pain Relevance 0.04

General Comments

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