INT319426

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.39
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRISP3) proteinaceous extracellular matrix (CRISP3) molecular_function (CRISP3)
Anatomy Link Frequency
CLC 4
CRISP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 10 76.72 Quite High
Inflammation 50 73.92 Quite High
chemokine 12 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 34 100.00 Very High Very High Very High
Chronic Sinusitis 28 100.00 Very High Very High Very High
Eosinophilic Esophagitis 10 85.08 High High
INFLAMMATION 54 73.92 Quite High
Rhinitis 124 63.92 Quite High
Disease 46 60.64 Quite High
Hypersensitivity 14 52.24 Quite High
Eczema 62 38.44 Quite Low
Nasal Polyps 12 28.80 Quite Low
Polyps 26 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our qRT-PCR results for CCL13, CCL18, CRISP3, EMR3, and IL1RL1 (ST2) (Figure 2) and the increased presence of CLC (Figure 3) and CCL18 [17] protein in separately collected airway specimens from CRS or asthmatic patients, in accordance with their increased mRNA levels in our aCRSwNP patients, further support the validity of our exon array data.
Positive_regulation (increased) of Localization (presence) of CRISP3 in CLC associated with asthma and chronic sinusitis
1) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.60 Pain Relevance 0.13
Our qRT-PCR results for CCL13, CCL18, CRISP3, EMR3, and IL1RL1 (ST2) (Figure 2) and the increased presence of CLC (Figure 3) and CCL18 [17] protein in separately collected airway specimens from CRS or asthmatic patients, in accordance with their increased mRNA levels in our aCRSwNP patients, further support the validity of our exon array data.
Positive_regulation (increased) of Localization (presence) of CRISP3 in CLC associated with asthma and chronic sinusitis
2) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.80 Pain Relevance 0.13

General Comments

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