INT319438

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.20
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL22) extracellular space (CCL22) extracellular region (CCL22)
cell-cell signaling (CCL22)
Anatomy Link Frequency
Th2 cells 1
neutrophils 1
CCL22 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 7 99.98 Very High Very High Very High
Inflammation 31 97.16 Very High Very High Very High
cytokine 2 84.08 Quite High
Inflammatory response 2 47.76 Quite Low
imagery 2 5.92 Low Low
aspirin 5 5.00 Very Low Very Low Very Low
backache 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rhinitis 62 97.68 Very High Very High Very High
INFLAMMATION 33 97.16 Very High Very High Very High
Osteomyelitis 22 96.48 Very High Very High Very High
Nasal Polyps 6 94.96 High High
Chronic Sinusitis 14 94.12 High High
Eczema 31 90.76 High High
Malignant Neoplastic Disease 15 85.28 High High
Apoptosis 2 83.12 Quite High
Cancer 2 82.56 Quite High
Lymphatic System Cancer 26 82.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCL18 and CCL22 are associated with chemoattraction of Th2 cells, which further amplify eosinophilic inflammation.
CCL22 Binding (associated) of in Th2 cells associated with rhinitis and inflammation
1) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.06 Pain Relevance 0.24
RS cells secrete interleukin-8 (IL-8) which serves as a chemoattractant for neutrophils, and express multiple chemokine ligands including CCL5, CCL17 and CCL22, which attract certain T-cell subsets [9].
CCL22 Binding (ligands) of in neutrophils associated with chemokine
2) Confidence 0.16 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2907869 Disease Relevance 1.14 Pain Relevance 0.12

General Comments

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