INT319556

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr) cytosol (Jun) nucleus (Jun)
DNA binding (Jun) transcription factor binding (Jun)
Anatomy Link Frequency
striatum 3
Jun (Mus musculus)
gr (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 7 86.44 High High
cocaine 19 78.44 Quite High
sodium channel 1 58.88 Quite High
addiction 14 52.36 Quite High
antagonist 8 31.04 Quite Low
Morphine 18 19.36 Low Low
Dopamine 6 5.20 Low Low
Nicotine 9 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
opiate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 8 64.32 Quite High
Aids-related Complex 3 5.00 Very Low Very Low Very Low
Drug Dependence 3 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Brain Disease 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since AP-1 is a potent repressor of GR activity [86], it seems that GR-mediated effects of HPA activation on gene transcription in the striatum after psychostimulant administration may have been inhibited by previous induction of the AP-1 complex proteins due to D1R activation.
Positive_regulation (induction) of AP-1 in striatum Negative_regulation (inhibited) of Positive_regulation (activation) of GR-mediated in striatum
1) Confidence 0.05 Published 2010 Journal Genome Biol Section Body Doc Link PMC2898085 Disease Relevance 0.17 Pain Relevance 0.24

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox