INT319559

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Creb1, Srf) DNA binding (Creb1, Srf) transcription factor binding (Creb1, Srf)
mitochondrion (Creb1) endoplasmic reticulum (Srf) cytoplasm (Srf)
Creb1 (Mus musculus)
Srf (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 19 89.52 High High
Glutamate receptor 1 34.08 Quite Low
Morphine 18 5.00 Very Low Very Low Very Low
addiction 14 5.00 Very Low Very Low Very Low
Nicotine 9 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Opioid 7 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
opiate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 3 58.32 Quite High
Stress 8 5.00 Very Low Very Low Very Low
Drug Dependence 3 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Brain Disease 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using bioinformatic analyses, we were able to postulate a role of the CREB and SRF transcription factors as main regulators of IEGs, which has been suggested previously [62,63].
CREB Spec (postulate) Regulation (role) of SRF
1) Confidence 0.28 Published 2010 Journal Genome Biol Section Body Doc Link PMC2898085 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

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