INT319564

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (SHOX)
SHOX (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 12 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Growth Problems 300 99.26 Very High Very High Very High
Growth Hormone Deficiency 21 94.00 High High
Congenital Anomalies 3 83.24 Quite High
Cadaver 3 82.72 Quite High
Syndrome 6 79.92 Quite High
Intrauterine Growth Retardation 3 79.44 Quite High
Turner's Syndrome 6 75.88 Quite High
Immunodeficiency 3 69.36 Quite High
Disease 3 22.40 Low Low
Hypoglycemia 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An example of this situation is a recent report of a child with ISS who was ultimately diagnosed with a deletion in exon 5 of the Short Homeobox X (SHOX) gene.4

A short history of GH therapy

Negative_regulation (deletion) of Gene_expression (exon) of SHOX associated with growth problems
1) Confidence 0.35 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2898102 Disease Relevance 1.43 Pain Relevance 0
In an analysis of 68 patients with ISS, one female patient was identified who had a normal karyotype but a deletion of one SHOX allele.69
Negative_regulation (deletion) of Gene_expression (allele.69) of SHOX associated with growth problems
2) Confidence 0.35 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2898102 Disease Relevance 0.80 Pain Relevance 0
An example of this situation is a recent report of a child with ISS who was ultimately diagnosed with a deletion in exon 5 of the Short Homeobox X (SHOX) gene.4

A short history of GH therapy

Negative_regulation (deletion) of Gene_expression (exon) of Short Homeobox X associated with growth problems
3) Confidence 0.35 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2898102 Disease Relevance 1.43 Pain Relevance 0

General Comments

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