INT31964

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Context Info
Confidence 0.65
First Reported 1986
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.63
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpc6) plasma membrane (Trpc6) transmembrane transport (Trpc6)
Anatomy Link Frequency
diaphragm 1
blood vessels 1
Trpc6 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 100.00 Very High Very High Very High
endometriosis 3 99.42 Very High Very High Very High
TRP channel 100 91.40 High High
Hippocampus 4 67.60 Quite High
Dismenorea 1 50.00 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 2 6 99.42 Very High Very High Very High
Adhesions 3 92.48 High High
Nephrotic Syndrome 8 89.84 High High
Sprains And Strains 34 59.68 Quite High
Hot Flashes 1 51.84 Quite High
Reprotox - General 1 1 50.00 Quite Low
Disease 15 43.68 Quite Low
Coronary Heart Disease 4 25.68 Quite Low
Targeted Disruption 2 21.68 Low Low
Renal Disease 6 19.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cellular localization of TRPC3, TRPC5 and TRPC6 mRNAs
Localization (localization) of TRPC6
1) Confidence 0.65 Published 2006 Journal BMC Genomics Section Body Doc Link PMC1557673 Disease Relevance 0 Pain Relevance 0.16
TRPC6 has also been localized to the slit diaphragm and a recent study identified proteins associated with TRPC5 and TRPC6 [41].
Localization (localized) of TRPC6 in diaphragm
2) Confidence 0.61 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.26 Pain Relevance 0
Using in situ hybridization experiments we were able to localize the mRNAs for TRPC3 and TRPC6 in cardiac muscle cells but not in the endothelium of cardiac blood vessels.
Neg (not) Localization (localize) of TRPC6 in blood vessels
3) Confidence 0.61 Published 2006 Journal BMC Genomics Section Body Doc Link PMC1557673 Disease Relevance 0.06 Pain Relevance 0
Eight menstrually cycling women with proven endometriosis were treated with a delayed-release preparation of the superactive agonist D-Trp-6-LH-RH in biodegradable microcapsules, administered intramuscularly at intervals of 16 to 36 days for a period of 3 to 5 months.
Localization (release) of D-Trp-6-LH-RH associated with endometriosis and agonist
4) Confidence 0.35 Published 1986 Journal Int. J. Fertil. Section Abstract Doc Link 2908272 Disease Relevance 0.30 Pain Relevance 0.14

General Comments

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