INT319680

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Keap1, Nfe2l2) cytoplasm (Keap1, Nfe2l2) endoplasmic reticulum (Keap1)
plasma membrane (Nfe2l2) DNA binding (Nfe2l2)
Keap1 (Mus musculus)
Nfe2l2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 82.64 Quite High
Disease Link Frequency Relevance Heat
Stress 46 99.96 Very High Very High Very High
Aging 2 62.56 Quite High
Cancer 12 62.16 Quite High
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under conditions of oxidative stress, KEAP1 loses its ability to limit NRF2 protein accumulation and to block NRF2 from transcribing its target genes.
KEAP1 Negative_regulation (loses) of Positive_regulation (accumulation) of NRF2 associated with stress
1) Confidence 0.36 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2898415 Disease Relevance 0.47 Pain Relevance 0.08
Under conditions of oxidative stress, KEAP1 loses its ability to limit NRF2 protein accumulation and to block NRF2 from transcribing its target genes.
KEAP1 Negative_regulation (limit) of Positive_regulation (accumulation) of NRF2 associated with stress
2) Confidence 0.36 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2898415 Disease Relevance 0.47 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox