INT319728

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crebbp, Ep300) DNA binding (Crebbp, Ep300) transcription factor binding (Crebbp, Ep300)
cytoplasm (Crebbp, Ep300) cell proliferation (Crebbp) transferase activity, transferring acyl groups (Ep300)
Anatomy Link Frequency
nucleus 2
Crebbp (Rattus norvegicus)
Ep300 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 29 84.00 Quite High
ischemia 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 23 84.00 Quite High
Hemorrhagic Shock 23 73.64 Quite High
Pneumonia 7 67.72 Quite High
Shock 8 60.32 Quite High
Lung Injury 4 22.00 Low Low
Injury 7 15.92 Low Low
Adult Respiratory Distress Syndrome 8 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Reperfusion Injury 4 5.00 Very Low Very Low Very Low
Hemorrhage 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Once in the nucleus, the p65 subunit is phosphorylated at serine 276, which enhances its ability to recruit CBP and p300 and subsequently bind to DNA.36,37 Here, HSPTX-resuscitated animals displayed a marked reduction in nuclear phosphorylated NF-?
Positive_regulation (enhances) of CBP Binding (recruit) of p300 in nucleus
1) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2898548 Disease Relevance 0.36 Pain Relevance 0.11

General Comments

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