INT31990
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The severity of fALS thus is related to mutation-induced increases in SOD1 aggregation propensity. | |||||||||||||||
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Transgenic flies expressing increased Cu/ZnSOD and catalase [22] displayed extended lifespan. | |||||||||||||||
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Induction of HLA-B27 heavy chain-homodimers after dendritic cell stimulation | |||||||||||||||
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A dose-dependent increase in MDA levels and SOD activity was also observed, which indicated a link between oxidative stress and nephrotoxicity. | |||||||||||||||
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The results indicated that the increase in SOD activity in the inflammatory periodontal tissue is associated with oxidative stimulation in periodontitis patients [13]. | |||||||||||||||
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SOD activity increases remarkably in irreversible pulpitis while it decreases significantly in the gingival tissue close to the deep periodontal pocket [6-8]. | |||||||||||||||
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Studies in patients with liver disease have shown that silymarin increases superoxide dismutase (SOD) activity of lymphocytes and erythrocytes, as well as the expression of SOD in lymphocytes. | |||||||||||||||
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We expanded upon these studies with a larger set of fALS-causing SOD1 mutations as well as larger patient cohorts. | |||||||||||||||
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The ChitiDobson equation results for all fALS-causing SOD1 mutations with patients' survival data also were evaluated in a univariate Cox proportional hazard model (Table 3). | |||||||||||||||
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However, a trend towards a significant group × time interaction (p = 0.06) was revealed with subsequent post-hoc analysis indicating that although SOD levels increased over time. | |||||||||||||||
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After SM administration GSH and AA significantly increase and SOD activity was significantly enhanced. | |||||||||||||||
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HSA NP-transfected cells exhibited enhanced SOD1 activity that was 5 fold higher than untreated cells, indicating the overexpression of the functional gene. | |||||||||||||||
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Levels of Cu/Zn superoxide dismutase were increased in wound tissue from mice treated with 6, 8 dithio-UA compared to vehicle-treated mice, suggesting that the UA analog enhances endogenous cellular antioxidant defenses. | |||||||||||||||
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R1-STAT1 complex seems to be internalized and translocated to the nucleus, where the activated STAT1 homodimer binds to DNA at GAS elements and induces the first wave of responses [204,207-211]. | |||||||||||||||
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Our previous work using a similar training stimulus indicated that this effect was due to a training induced induction of the anti-oxidant enzymes, catalase and Cu/Zn superoxide dismutase [61]. | |||||||||||||||
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Serum SOD activity was higher in CC than in TT genotype of SOD2 gene (p < 0,05) and higher in AA than in CC genotype of SOD1 gene (p < 0,05). | |||||||||||||||
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Since 2000, a proprietary melon juice concentrate containing high level of SOD has been developed, its use as a dietary supplement has been a new subject of interest and its antioxidant and anti-inflammatory properties have been demonstrated [8]. | |||||||||||||||
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This HP was increased in SOD1-TG and its over-expression may lead or represent impaired cytoskeleton and/or mRNA splicing in hippocampus, which in turn may be in agreement with cytoskeleton and mRNA splicing deficits observed in DS brain [41,42]. | |||||||||||||||
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An abnormal gall bladder ejection fraction could be an indication for cholecystectomy, while a fatty meal-stimulated bile duct dilatation mandates SOM and possible sphincterotomy.[47] Of the patients who have documented SOD and an intact gall bladder and who are treated with sphincterotomy, first, only 43% have long-term pain relief; some additional patients eventually show response to cholecystectomy.[48] | |||||||||||||||
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The SOD activity was evaluated using an SOD Assay Kit - WST (Dojindo Laboratories, Kumamoto, Japan) according to the manufacturer's instruction, and an ELISA reader (Model-680®) at 450 nm. | |||||||||||||||
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