INT319973

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (App, Mapk12) mitochondrion (Mapk12) Golgi apparatus (App)
extracellular matrix organization (App) DNA binding (App) cell adhesion (App)
Anatomy Link Frequency
mast cells 2
App (Mus musculus)
Mapk12 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 76.80 Quite High
dexamethasone 18 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
corticosteroid 9 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Piles 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 100.00 Very High Very High Very High
Asthma 22 95.48 Very High Very High Very High
Disease 7 92.32 High High
Cancer 1 83.36 Quite High
Rhinitis 5 77.48 Quite High
INFLAMMATION 40 76.80 Quite High
Hypersensitivity 65 73.80 Quite High
Adverse Drug Reaction 2 53.36 Quite High
Venous Insufficiency 2 45.92 Quite Low
Diarrhoea 1 20.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To receive more insight into the mode of action, further research is required to explain the influence of beta-escin on intracellular signaling cascades in mast cells, such as mitogen- or stress-activated protein kinase pathways, on calcium influx and on transcription factors such as NF-?
beta-escin Regulation (influence) of Gene_expression (pathways) of stress-activated protein kinase in mast cells associated with stress
1) Confidence 0.02 Published 2010 Journal BMC Immunol Section Body Doc Link PMC2898835 Disease Relevance 0.98 Pain Relevance 0.04

General Comments

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