INT320021

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkaca, Kcnma1) nucleoplasm (Prkaca) mitochondrion (Prkaca)
endoplasmic reticulum (Kcnma1) Golgi apparatus (Prkaca) protein complex (Prkaca)
Prkaca (Rattus norvegicus)
Kcnma1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 43 98.16 Very High Very High Very High
ischemia 24 84.80 Quite High
Angina 2 75.12 Quite High
adenocard 1 73.36 Quite High
MU agonist 2 64.00 Quite High
opioid receptor 4 51.20 Quite High
Opioid 3 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 23 84.80 Quite High
Organ Transplantation 4 82.56 Quite High
Stroke 2 75.76 Quite High
Cv General 3 Under Development 2 75.12 Quite High
Myocardial Infarction 2 73.76 Quite High
Reperfusion Injury 3 5.00 Very Low Very Low Very Low
Contracture 2 5.00 Very Low Very Low Very Low
Ischemic Contracture 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Xi et al. could show that morphine prevents mPTP opening by inactivation of GSK3beta.34 Our results showing that morphine confers preconditioning through activation of mKCa channels and the fact that enzymes like PKA regulate mKCa channel activation suggest future directions for investigating the underlying mechanism of morphine-induced cardioprotection.
PKA Regulation (regulate) of Positive_regulation (activation) of channel associated with morphine
1) Confidence 0.00 Published 2010 Journal Can J Anaesth Section Body Doc Link PMC2899019 Disease Relevance 0.54 Pain Relevance 1.00

General Comments

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