INT320029

Context Info Confidence 0.03 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular matrix organization (SOX9) protein complex assembly (SOX9) protein complex (SOX9) signal transduction (SOX9) extracellular region (COL7A1) nucleolus (SOX9)

SOX9 (Homo sapiens) COL7A1 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 4 5.00 backache 3 5.00 Inflammation 1 5.00 Sciatica 1 5.00

Disease Link Frequency Relevance Heat Aging 5 42.68 Stress 5 5.00 Intervertebral Disk Degeneration 3 5.00 Low Back Pain 3 5.00 Injury 2 5.00 Intervertebral Disk Displacement 2 5.00 Volume Depletion And Dehydration 2 5.00 Apoptosis 2 5.00 Recurrence 2 5.00 Fibrosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

They found that collagen synthesis could be enhanced by over-expression of BMP-13 and of the transcription factor Sox9 [131].

Gene_expression (expression) of transcription factor Sox9 Positive_regulation (enhanced) of Gene_expression (synthesis) of collagen

1) Confidence 0.03 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2899423 Disease Relevance 0 Pain Relevance 0

General Comments

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